Publication
2022
Shrestha, P. & Klann, E. Spatiotemporally resolved protein synthesis as a molecular framework for memory consolidation. Trends in Neurosciences.TINS 1788, February 2022. doi:10.1016/j.tins.2022.01.004
2020
Shrestha, P.*, Ayata, P.*, Vidal, P.H., Gastone, A., Heintz, N. & Klann, E. Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation. Nature Neuroscience 2020. 23(2):281-292. doi: 10.1038/s41593-019-0568-z
2020
Shrestha, P*., Shan, Z., Marmacz, M., Zerihoun, A.T., Juan, C-Y., San Agustin Ruiz, K., Pelletier, J., Heintz, N. & Klann, E*. Amygdala inhibitory neurons as loci for translational control of emotional memories. Nature 2020. 586(7829):407-411. doi: 10.1038/s41586-020-2793-8
2016
Shrestha, P. & Klann, E. Lost memories found. Nature 531 (7595), 450-451. doi:10.1038/nature17312
2015
Shrestha, P., Mousa, A. & Heintz, N. Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors. eLife 2015; e08752. doi: 10.7554/eLife.08752
2015
Previewed by: Park, C.S. & Yang, X.W. Neuropsychiatric disorders: probing stress and depression circuits with a disease gene. eLife 2015; e10829. doi: 10.7554/eLife.10829
2018
Doyle, J.P., Dougherty, J.D., Heiman, M., Schmidt, E.F., Stevens, T.R., Ma, G., Bupp, S., Shrestha, P., Shah, R.D., Doughty, M.L., Gong, S., Greengard, P. & Heintz, N. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell 2008 Nov 14: 135(4): 749-62. doi: 10.1016/j.cell.2008.10.029
Preprint
Shrestha, P., Ayata, P., Herrero-Vidal, P., Longo, F., Gastone, A., Ledoux, J.E., Heintz, N., & Klann, E. Chemogenetic evidence that rapid neuronal de novo protein synthesis is required for consolidation of long-term memory. bioRxiv 2019. doi: 10.1101/704965
Preprint
Shrestha, P., Shan, Z., Marmarcz, M., Ruiz, K.S.A., Zerihoun, A.T., Juan, C-Y., Herrero-Vidal, P.M., Pelletier, J., Heintz, N., & Klann, E. De novo protein synthesis in distinct centrolateral amygdala interneurons is required for associative emotional memories. bioRxiv 2020. doi: 10.1101/2020.04.08.028233